General
The usual caveats above about using a consistent compiler apply.
Using clang from the base system
See clang and the base system.
Using clang from pkgsrc in the same prefix
Building
You can build clang from pkgsrc (lang/clang). However, it needs gcc 6 or higher and cmake.
Configuration
Once built, you should (\todo test this) be able to set:
PKGSRC_COMPILER= clang
CLANGBASE= /usr/pkg
Perhaps, but probably not, you might set:
HAVE_LLVM= yes
Rebuilding clang and dependencies with clang
After building, you will have clang and everything it depends on built with some combination of the base system compiler, and, if that's < gcc6, also gcc6. This violates the normal rule about using the same complier. One can "make replace" those packages to recover, as long as nothing goes wrong in the meantime. It might be best to "pkg_admin set rebuild=YES" of all those packages (perhaps "*" if this is done before building anything else) and then "pkg_rolling-replace uv".
In particular, libtool embeds paths to compiler objects, and at least that should be rebuilt. It is unclear if clang itself needs rebuilding.
Using clang from pkgsrc in a different prefix
This section is completely untested
Bootstrap pkgsrc as e.g. /usr/pkg-clang, and in that prefix build clang.
In /usr/pkg, remove all packages and configure
PKGSRC_COMPILER= clang
CLANGBASE= /usr/pkg-clang
and then build packages.